Death With Dignity
Pentobarbital, also known as pentobarbitone, is a short-acting barbiturate. In high doses, pentobarbital causes death by respiratory arrest. In the United States, the drug has been used for executions of convicted criminals. Lundbeck (one of many manufacturers) does not permit its sale to prisons or corrections departments to carry out the death penalty. Abbott Pharmaceuticals‘ brand of pentobarbital, Nembutal, which was available in 50 and 100 mg yellow capsules, was discontinued in 1999. Prescribed for insomnia, it has been largely replaced by the benzodiazepine family of drugs. Nembutal was widely abused and known on the streets as “yellow jackets” due to their yellow capsule. Pentobarbital in pill form is no longer available. The death of Marilyn Monroe in 1962 was ruled as probable suicide due to an overdose of Nembutal. Kenneth Halliwell‘s death is also attributed to an overdose of Nembutal capsules.
Currently in Oregon, secobarbital is the medication most commonly prescribed for physician-assisted suicide, followed by pentobarbital. The lethal dose prescribed is typically 9 g of secobarbital in capsules or 10 g of pentobarbital liquid, to be consumed at one time.[4–6] The contents of the secobarbital capsules or the pentobarbital liquid should be mixed with a sweet substance such as juice to mask the bitter taste. Until the time of use, the medication must be stored out of reach of children and kept away from others to prevent unintentional overdose or abuse.
The pharmacist or physician should instruct patients to take the lethal dose on an empty stomach to increase the rate of absorption.  The typical dose of pentobarbital as an oral hypnotic for adults is 100–200 mg at bedtime, and that of secobarbital is 100 mg orally at bedtime buy Nembutal oral solution
Pentobarbital is a short-acting barbiturate, now rarely used in suicide attempt because it is no longer prescribed for medical purposes in most countries. Only a few cases have been published in the last decade, mostly among veterinarians because this drug is used as euthanasia agent. Pentobarbital is indeed the drug of choice for assisted-suicide. Pentobarbital is a weak acid with high lipid-solubility. After oral absorption, it is readily absorbed with an onset of action of 10 to 60 minutes. The degree of protein binding is about 45 to 70% and the volume of distribution is 0.5 to 1L/Kg. The plasma half-life for pentobarbital is 15 to 50 hours and appears to be dose-dependent. Renal excretion is negligible (< 1%). Pentobarbital is metabolized by the liver and excreted in the urine as inactive metabolites. read more
Nembutal belongs to the class of drugs known as barbiturates. shop here Invented in the late 19th century, these act to depress various aspects of brain function. Barbiturates have been used for many purposes, including to treat sleep disorders, epilepsy and traumatic brain injury – as well as in anaesthesia and psychiatry. Read more
Pentobarbital is readily available without prescription on the Internet. Although there is little public awareness about this drug, current mediatisation of assisted-suicide could lead to an increased interest from suicide attempters. Supportive care is the cornerstone of medical management. contact us